Human Serum – Normal, Heat Inactivated
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Normal human serum is prepared from units of U.S.-sourced plasma, utilizing healthy male and female donors of all blood groups.
Heat-inactivated human serum is frequently used in immunological applications. The most common objective of heat inactivation is to destroy heat-labile components such as complement that may have an adverse effect on the performance of some cell cultures or in some immunological assays. The inactivation process involves raising the temperature to 56°C for 30 minutes under controlled conditions.
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Each approved donor unit is tested and found non-reactive for HBsAg (Hepatitis B Surface Antigen), HCV (Hepatitis C Virus), HIV-1 (Human Immunodeficiency Virus type 1), HIV-2 (Human Immunodeficiency Virus type 2), HIV-1 antigen or HIV-1 NAT, and syphilis by FDA approved methods. The individual donor units collected are then converted into serum by defibrinating the plasma, pooled, filtered, and bottled. The final serum product undergoes extensive quality control testing before it is released for distribution.
- Form: Liquid
- Product Size: 100 ml and 10ml
- Sterility Testing: Pass
- Suitability: Laboratory research applications
- Shipping conditions: On dry ice
- Storage conditions: -5 to -20°C, protected from light
Human serum products should always be considered potentially infectious and handled accordingly. Although all of the source plasma units are tested and have been found negative for several virus antibodies and antigens, no known test method can offer complete assurance that products derived from human blood will not transmit infectious disease.